Joining Novo Holdings

A career with Principal Investments

Be part of driving sustainable growth in healthcare and life sciences

Principal Investments is the private equity buyout platform of Novo Holdings, investing in leading, growth-oriented healthcare and life science companies across Europe and North America. We look to support leading management teams delivering sustainable, long-term growth and value creation, with a particular focus on fuelling innovation and growth along the healthcare value chain. We primarily invest within life science services, life science tools and diagnostics, MedTech and healthcare IT.

Principal Investments seeks to invest $100–500+ million in each transaction. Beyond capital, we offer engaged ownership and access to a broad network of seasoned healthcare and life sciences executives and specialists, along with deep sector insights and expertise on a global scale. We have a flexible mandate in terms of investment duration and modality, predominantly targeting control and co-control situations but also open to significant minority positions with appropriate governance rights, allowing us to deploy our engaged ownership approach.

Established in 2013, Principal Investments today operates out of Copenhagen and Boston. As of year-end 2024, 36 employees work in Principal Investments. Team members have a strong background within healthcare-focused private equity investing, tier 1 investment banking and/or consulting. We are all driven by a shared strategic vision of delivering strong financial returns by helping management teams and companies reach their full potential, while also delivering positive societal impact through our investments.

Join our team of dedicated PE healthcare investors

Our culture in Principal Investments is centred around the overall Novo Holdings values of Performance, Respect and Responsibility. We empower our team members across all levels, and expect them to deliver outstanding performance while displaying impeccable integrity and collaboration. We value thoughtfulness and quality, and we believe that diversity of thought and background enhance our performance.

We prioritise professional development and involve our junior employees in management interactions and Investment Committee meetings, at which they are often given the opportunity to present and engage in the decision-making process. A new-joiner to Principal Investments will gain exposure to a full range of investment and asset management processes relatively early in their career.

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Jessica Li

“The people at Novo Holdings truly set it apart. Being surrounded by smart, driven, and down-to-earth team members inspires everyone to excel while also promoting a strong sense of collaboration and camaraderie both in the office and outside of work. The firm’s dedication to learning and growth, with a focus on mentorship at all levels, has empowered me to expand my skills and take on new challenges.”

Jessica Li

Vice President, Principal Investments

Our investment mandate and assets 

By the end of 2024, Principal Investments had 16 portfolio companies of which eight are headquartered in Europe and eight in North America, with a total portfolio value of DKK 99 billion.

Johan Hueffer

“Working within the Principal Investments team at Novo Holdings is highly rewarding. Against the backdrop of a fast-growing, high profile investment organisation, the team has successfully used its unsurpassed life sciences sector insights to capitalise on compelling opportunities to acquire and invest in leading companies around the world. Working with outstanding management teams, we relish the prospect of further enhancing the market position and financial performance of our portfolio companies. It’s a very exciting team to be a part of.”

Johan Hueffer

Senior Partner, Principal Investments