Principal Investments

Sizeable investments in leading life science companies

Christoffer Søderberg

"We invest in life science companies whose key sources of value creation are innovation and growth. Our investments come with an engaged and supportive approach to help companies realise their full potential"

Christoffer Søderberg

Managing Partner, Principal Investments


The Principal Investments team targets investments in well-established life science companies with leading positions in attractive market segments, benefiting from strong underlying growth drivers. Principal Investments operates out of Denmark (Copenhagen), the UK (London) and the US (Boston), executing control, co-control and significant minority investments. Novo Holdings’ Asia investment team, based in Singapore, works in close collaboration with our teams in Europe and the US. We seek to invest USD 100-500+ million in each transaction, always with an engaged, supportive ownership agenda in mind.

In addition to capital and engagement, an investment from Novo Holdings also provides access to our extensive network within the life science industry. We use our experience and expertise from our ownership of world-leading life science companies to actively support a board and management in realizing their strategic ambitions.

At the end of 2023, the Principal Investments portfolio comprised 17 companies, with a total value of DKK 75 billion.

Principal Investments key figures


In realised total proceeds in 2023


Number of portfolio companies in 2023


Assets under Management by the end of 2023

Go to annual report

Our Principal Investments Portfolio


Meet our team

Our team, based in Europe and the US, consists of investment professionals with a diverse set of backgrounds from private equity, banking, consulting, and industry.

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